Microfluidised sperm extraction chip used in the microinjection method, known as IVF…
It is designed with the aim of ensuring the healthy separation of sperm cells, which are in good physiological and morphological condition and have a much lower rate of DNA fractures, from other low-quality, dead and immature sperm cells, without using techniques that can cause physical damage to healthy and living cells. Before artificial fertilisation occurs, the semen sample, which means rotation, is centrifuged with high-speed precipitation in order to separate sperm from sperm fluid.
Experts, who think that sperm may be damaged while the procedure is taking place, state that minimising this risk is due to this microfluidic chip. To distinguish healthy and vibrant sperm from other poor-quality sperm, the sperm fluid is injected into a channel inside the chip that is less than half a millimetre wide. Live and healthy sperms move from the channel inside the chip to the exit, and the poor quality or damaged sperms are separated. Thus, the proportion of live and healthy sperm in the sperm fluid is increased from 45 percent to 98 percent. (This process is scientifically proven.)
Scientists emphasised that men with infertility problems have very few healthy sperms among tens of thousands of unhealthy sperms in their sperm fluid, and they emphasised the difficulty of weeding unhealthy sperms and healthy sperms, and they recorded that sorting is much easier thanks to this process.
According to data from the World Health Organisation, 70 million couples around the world have to deal with infertility. Today, one third of the infertility problems experienced are male-caused. Microinjection, i.e. ICSI, provides the best solution to the male infertility problem among all treatment approaches. It has been stated that the most important thing in microinjection treatment is achieved by selecting high quality sperm.
In IVF (In Vitro Fertilisation) and ICSI (Intracellular Sperm Injection) techniques, the morphology and motility of sperm indicate the sperm selection parameter.
However, it has been seen that today’s standard techniques are not sufficient to select sperms suitable for the parameters mentioned. In addition, it has been stated that decomposition techniques (centifiguration) based on density cause DNA damage. The swimming of the sperm in the sediment form, which is obvious from within, to the fresh environment, is based on the flotation technique. Both techniques are insufficient in semen samples with a DNA fracture rate.
It has been stated that the most important thing in microinjection treatment is achieved by selecting high quality sperm.
Microfluent technologies are used to obtain healthy and live sperm in an IVF protocol for IVF treatment.
On the way that the sperm goes to reach the egg, the sperm goes through the microducts. During fertilisation, this environment was recreated in these systems on the microchip. With the understanding of microfluidic technology, it has been determined that it offers a selection mechanism suitable for sperm physiology. The clinical techniques currently practised depend on the employee and it is known how difficult these techniques are. Microfluidic technology, which has high efficiency and allows healthy sperm extraction, is a product of the technique we are using. With the microchip method used, the sperms that are motile are easily isolated in a narrow microfluidised environment.
It is suitable for use in ROMAN™ and toROMAN™ IVF centres, andrology laboratories, treatment centres and medical laboratories to help reproduction.
With ROMAN™ and toROMAN™ microfluidic systems, it aims to separate the least exposed sperm to free oxygen radicals, which are the fastest and healthiest genetic material from the semen sample without requiring any pre-treatment, and the use of these separated sperms in treatments such as IVF (In Vitro Fertilisation) and ICSI (Intro Stoplasmic Sperm Injection) and to increase the success rate in IVF.
Microfluidic technology, which has high efficiency and allows healthy sperm extraction, is a product of the technique we are using.
Microfluidic technology, which has high efficiency and allows healthy sperm extraction, is a product of the technique we are using.
Many centres use our products both in our country and in the world. Scientific studies are prepared in this field with many countries in Europe, Russia, America and many centres in Turkey and evaluated with the data obtained.
Our products are manufactured in accordance with the medical device regulation of the Ministry of Health of the Republic of Turkey within the framework of European Union Standards.
