Microchip Vaccination

Microfluidic sperm extraction chips used in the IUI method,

Vaccination with its known name…

It is designed to ensure that sperm, which are in better morphological and physiological condition and have a much lower rate of DNA fractures, from other dead, immature and low-quality sperm cells without using techniques that can cause physical damage to living, healthy cells.

Before artificial fertilisation, the semen sample is centrifuged (precipitation with high-speed rotation) to separate sperm and sperm fluid. Stating that sperm can be damaged during this process, experts state that this risk is minimised thanks to this microfluidic chip. To separate sperm; sperm fluid is injected into a channel inside this chip that is smaller than half a millimetre wide, and healthy sperms float to the exit from the channel in the chip, separating healthy sperm from dead or damaged sperms. After this procedure, it was determined that the rate of healthy sperm in the sperm fluid increased from 45 percent to 98 percent. The scientists stated that there are only a few healthy sperms among millions of unhealthy sperm in the sperm fluid of men who are found to be infertile and that the process of sorting is very difficult, and that the extraction process becomes easier thanks to this method.

After this procedure, it was determined that the rate of healthy sperm in the sperm fluid increased from 45 percent to 98 percent.

According to the estimates of the World Health Organisation, 70 million couples worldwide suffer from infertility. According to current information, one-third of infertility cases are male-only. Among all treatment approaches, assisted reproductive treatments (ARTs), such as intracellular sperm injection (ICSI), have been determined to be the best solution to male infertility. It has also been shown by pregnancy rates that the key point in ICSI treatment is to choose the healthiest sperm.

In in vitro fertilisation (IVF) and ICSI techniques, the sperm selection parameter is the motility and morphology of sperm. However, it has been observed that the current standard techniques are insufficient in selecting sperm with these parameters. It has also been shown that DNA damage occurs in the decomposition techniques that depend on the density difference. The floating technique is based on the movement among the sediment sperms swimming up, fresh. Both of these techniques are insufficient in semen samples with high DNA fracture rate.

According to the estimates of the World Health Organisation, 70 million couples worldwide suffer from infertility. According to current information, one-third of infertility cases are male-only. Among all treatment approaches, assisted reproductive treatments (ARTs), such as intracellular sperm injection (ICSI), have been determined to be the best solution to male infertility. It has also been shown by pregnancy rates that the key point in ICSI treatment is to choose the healthiest sperm.

In in vitro fertilisation (IVF) and ICSI techniques, the sperm selection parameter is the motility and morphology of sperm. However, it has been observed that the current standard techniques are insufficient in selecting sperm with these parameters. It has also been shown that DNA damage occurs in the decomposition techniques that depend on the density difference. The floating technique is based on the movement among the sediment sperms swimming up, fresh. Both of these techniques are insufficient in semen samples with high DNA fracture rate.

Sperm travels on microchannels on the way to the egg. It is prepared in a microchip similar to this environment in natural fertilisation.

Our products are manufactured in accordance with the medical device regulation of the Ministry of Health of the Republic of Turkey within the framework of European Union Standards.